Major Developments

Isomorphic Labs – to Begin Human Trials for AI-Designed Drugs

Google- Backed Alphabet’s Isomorphic Labs, preparing to launch its first human clinical trials of drugs created using artificial intelligence.

This marks a huge step forward in how medicines are discovered and tested.

What Isomorphic Labs Is Doing

  • The company is using AI tools based on DeepMind’s AlphaFold, a powerful system that can predict how proteins fold and interact.
  • With this technology, Isomorphic Labs can design potential drug molecules much faster than traditional methods.
  • These drugs are mainly being developed to treat cancer and immune system disorders.
  • Colin Murdoch, president of Isomorphic Labs, confirmed that they’re “getting very close” to starting trials. The company expects its first AI-designed drug to enter human testing by the end of 2025.

How It Works

  • Instead of spending years in labs with trial-and-error testing, Isomorphic Labs uses AI models to:
  • Predict how proteins behave in the body
  • Identify drug molecules that might work well
  • Simulate how those molecules interact with the human body
  • This helps researchers zero in on promising treatments much faster.

Investment

In April 2025, the company raised $600 million from investors like Thrive Capital, GV (Google Ventures), and Alphabet itself.

They’ve also signed multi-year research deals with big pharmaceutical companies such as Eli Lilly and Novartis.

These partnerships allow them to co-develop drugs using their AI platform.

What’s Coming Next

  • The first drugs to enter human trials will be for cancer and immunological diseases.
  • The trials will take place in partnership with global pharma companies and may start by late 2025.
  • If successful, this would be one of the first real-world proofs that AI can create effective human medicines.

News Gist

Google-backed Isomorphic Labs is set to begin human trials for its AI-designed cancer and immune disorder drugs by late 2025.

Using DeepMind’s AlphaFold, the company aims to revolutionize drug discovery with faster, cheaper, and more targeted treatments.

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